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. 1972 Feb;5(2):169-71.
doi: 10.1128/iai.5.2.169-171.1972.

Photodynamic treatment of herpes keratitis

C Moore, C Wallis, J L Melnick, M D Kuns

Photodynamic treatment of herpes keratitis

C Moore et al. Infect Immun. 1972 Feb.

Abstract

Photodynamic inactivation of virus was tested as a potential therapeutic tool for herpesvirus-induced keratitis, which is a leading cause of blindness and disability. Experimental keratitis produced in rabbits by infection with herpesvirus isolated from a human periorbital lesion was treated with proflavine and light. The herpetic keratitis could be rapidly resolved by the dye-light treatment, whereas improvement was not seen in untreated rabbits, nor in those treated with light alone or dye alone.

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References

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