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. 1972 Nov;25(11):951-4.
doi: 10.1136/jcp.25.11.951.

The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis

W J Williams, E Pioli, D J Jones, M Dighero

The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis

W J Williams et al. J Clin Pathol. 1972 Nov.

Abstract

Circulating lymphocytes from 30 patients with sarcoidosis when stimulated in vitro with Kveim-induced macrophage migration factor, the Kmif test, produced a guinea-pig macrophage migration inhibition factor in 21 of 30 cases (70%). In those patients not on steroids the results showed a good correlation with the cutaneous Kveim test. One positive test was found in 16 normal subjects. Our results suggest that the Kmif test may prove a useful rapid alternative to the Kveim test.

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