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. 1972 Dec;23(6):881-7.

The antigen-binding characteristics of antibody pools of different relative affinity

M W Steward, R E Petty

The antigen-binding characteristics of antibody pools of different relative affinity

M W Steward et al. Immunology. 1972 Dec.

Abstract

The interstrain differences in relative affinity of mouse anti-HSA antibody previously shown by studies at equilibrium are also observed when rates of association and dissociation and avidity indices are measured. Marked differences are demonstrated in the binding characteristics of high and low relative affinity antibody to both protein and hapten antigens. These results are explained on the basis of heterogeneity of antibody-binding affinity.

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References

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