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. 1979 Jun 15;35(6):809-11.
doi: 10.1007/BF01968265.

Choleretic and cholestatic effects of infused bile salts in the rat

R Drew, B G Priestly

Choleretic and cholestatic effects of infused bile salts in the rat

R Drew et al. Experientia. .

Abstract

In rats, at low infusion rates taurocholate (TC), taurochenodeoxycholate (TCDC) and taurodeoxycholate (TCD) each produced an increase in bile flow of 20-50%. However, at high infusion rates (5-20 mumoles min-1kg-1) the cholestatic effects of the bile salts were revealed and the relative toxicity of the bile salts was seen to be TDC greater than TCDC greater than TC.

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