Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jun 15;35(6):809-11.
doi: 10.1007/BF01968265.

Choleretic and cholestatic effects of infused bile salts in the rat

R Drew, B G Priestly

Choleretic and cholestatic effects of infused bile salts in the rat

R Drew et al. Experientia. .

Abstract

In rats, at low infusion rates taurocholate (TC), taurochenodeoxycholate (TCDC) and taurodeoxycholate (TCD) each produced an increase in bile flow of 20-50%. However, at high infusion rates (5-20 mumoles min-1kg-1) the cholestatic effects of the bile salts were revealed and the relative toxicity of the bile salts was seen to be TDC greater than TCDC greater than TC.

PubMed Disclaimer

References

    1. Gut. 1971 Feb;12(2):145-52 - PubMed
    1. Can J Physiol Pharmacol. 1971 Dec;49(12):1078-91 - PubMed
    1. Eur J Pharmacol. 1973 Sep;23(3):270-5 - PubMed
    1. Naunyn Schmiedebergs Arch Pharmacol. 1974;285(2):165-74 - PubMed
    1. Am J Physiol. 1976 Sep;231(3):734-42 - PubMed