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. 1979 Jun 15;35(6):840-2.
doi: 10.1007/BF01968285.

Shape change reaction of platelets in protein-free medium: ultramorphology

M Graf, J G Richards, V Colombo, A Pletscher

Shape change reaction of platelets in protein-free medium: ultramorphology

M Graf et al. Experientia. .

Abstract

Transmission and scanning electron microscopy indicate that rabbit platelets incubated in protein-poor medium retain their reactivity to shape change-inducing agents such as 5-hydroxytryptamine, adenosine-5'-diphosphate and chlorpromazine. Such platelets may be used as models for drug-membrane interactions, e.g. in neuronal cells.

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