[Chromosome studies in couples with repeated abortions]
- PMID: 4678743
- DOI: 10.1007/BF00667668
[Chromosome studies in couples with repeated abortions]
Abstract
PIP: In a nonselected group of 26 women with 3 or more abortions and in 17 of the respective husbands, chromosomes from lymphocyte cultures were investigated. 6 persons were found to have abnormal chromosomes; in 3 women variations in the length of autosomes were found (46,XX,Gp+; 46,XX ,Gp-; 46,XX,Cq+). 1 woman showed a trisomy C mosaicism in 4% of the analyzed cells. A second one had in 4% of the mitoses a translocation mosaic with a B/D-translocation(46,XX/46,XX,t(Bq+; Dq-)). Another woman with normal karyotype showed in 3 different analyses an increased rate of secondary chromosome aberrations with a high percentage of exchanges.