doi: 10.1136/gut.20.5.394.
Endogenous prostaglandins in peptic ulcer disease
- PMID: 468069
- PMCID: PMC1412434
- DOI: 10.1136/gut.20.5.394
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Endogenous prostaglandins in peptic ulcer disease
Gut.
1979 May.
Abstract
Plasma concentrations of prostaglandins E and F have been measured by radioimmunoassay in patients undergoing diagnostic upper intestinal endoscopy. The results fail to support a previously reported deficiency of plasma PGE in duodenal ulcer patients. Plasma prostaglandin concentrations failed to correlate with the parameters of gastric secretion studied; and were unaffected by histamine H2-receptor blockade or the activity of duodenal ulceration. During combined pentagastrin and insulin secretory studies there was a significant correlation between the outputs of PGE and acid into gastric juice.
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