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Comparative Study
. 1979 Jun;24(3):679-84.
doi: 10.1128/iai.24.3.679-684.1979.

Purification and characterization of different types of exfoliative toxin from Staphylococcus aureus

A D Johnson, L Spero, J S Cades, B T de Cicco
Comparative Study

Purification and characterization of different types of exfoliative toxin from Staphylococcus aureus

A D Johnson et al. Infect Immun. 1979 Jun.

Abstract

Exfoliative toxin was isolated from strain DI of Staphylococcus aureus using carboxymethyl cellulose and hydroxylapatite chromatography. This purified toxin was compared with that produced by strain TA. The specific biological activity of the two toxins was the same, but they were serologically distinct. These strains have different loci (plasmid or chromosomal) for toxin production; differences were seen in molecular weight and amino acid composition. N-terminal amino acid sequences from the two strains showed significant homology using a single unit alignment shift.

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References

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