Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin
- PMID: 468382
- PMCID: PMC414401
- DOI: 10.1128/iai.24.3.958-961.1979
Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin
Abstract
A form of systemic tetanus with atypical symptoms was observed in mice injected in the left thigh with a mixture of tetanus toxin and antibody produced in guinea pigs against a fragment of toxin obtained from a subtilisin digest of the crystallized toxin. The mice did not show typical symptoms of the local tetanus such as convulsions or spastic paralysis of the injected limb.
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