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. 1973 Feb 10;1(5849):328-30.
doi: 10.1136/bmj.1.5849.328.

Abnormal excretion of corticosteroid sulphates in patients with breast cancer

P C Ghosh, E Lockwood, G W Pennington

Abnormal excretion of corticosteroid sulphates in patients with breast cancer

P C Ghosh et al. Br Med J. .

Abstract

In a preliminary study, the 24-hour urinary excretion of corticosteroid sulphates and free cortisol have been measured in a group of patients with breast cancer and compared with the excretion of the same compounds in a group of normal women of similar age. Excretion of corticosteroid sulphates in the breast cancer group was found to be markedly raised. In a small number of patients with localized cancer of sites other than the breast the level of corticosteroid sulphate was not raised. If proved metastases were present a noticeable rise was observed.

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