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. 1979 May;81(2):348-54.
doi: 10.1083/jcb.81.2.348.

Cytochalasin B inhibition of endothelial proliferation at wound edges in vitro

S C Selden 3rd, S M Schwartz

Cytochalasin B inhibition of endothelial proliferation at wound edges in vitro

S C Selden 3rd et al. J Cell Biol. 1979 May.

Abstract

Cytochalasin B prevents both migration and wound-associated replication when applied to wounded monolayers of bovine endothelium in tissue culture. The normal low background rate of replication in undisturbed areas of the cultures is not inhibited by cytochalasin B. These results suggest that some form of movement may be required for initiation of wound-associated replication by endothelial cells.

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