Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1973 Mar 16;179(4078):1131-3.
doi: 10.1126/science.179.4078.1131.

Cholesterol hydroperoxide formation in red cell membranes and photohemolysis in erythropoietic protoporphyria

A A Lamola, T Yamane, A M Trozzolo

Cholesterol hydroperoxide formation in red cell membranes and photohemolysis in erythropoietic protoporphyria

A A Lamola et al. Science. .

Abstract

3beta-Hydroxy-5alpha-hydroperoxy-Delta(6)-cholestene is produced in protoporphyrin-containing red blood cell ghosts irradiated with approximately 400-nanometer light in the presence of oxygen. Incorporation of this cholesterol photooxidation product into normal red blood cells leads to increased osmotic fragility and eventual hemolysis. These results may be relevant to photohemolysis associated with erythropoietic protoporphyria.

PubMed Disclaimer

LinkOut - more resources