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Clinical Trial
. 1973 Jul 14;3(5871):86-7.
doi: 10.1136/bmj.3.5871.86.

Reduction of absorption of paracetamol by activated charcoal and cholestyramine: a possible therapeutic measure

Clinical Trial

Reduction of absorption of paracetamol by activated charcoal and cholestyramine: a possible therapeutic measure

B Dordoni et al. Br Med J. .

Abstract

The absorption of an oral 2-g dose of paracetamol was markedly reduced by the simultaneous oral administration of either activated charcoal or cholestyramine but was only slightly reduced when the adsorbents were given 60 minutes after the paracetamol. Since the absorption of a larger dose of the drug will probably be slow, the administration of adsorbents may be of value even when delayed several hours.

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References

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