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. 1973 Feb;131(2):415-6.
doi: 10.1042/bj1310415.

Inhibition by acetaldehyde of the pyruvate dehydrogenase complex from ox brain and ox kidney

J P Blass, C A Lewis

Inhibition by acetaldehyde of the pyruvate dehydrogenase complex from ox brain and ox kidney

J P Blass et al. Biochem J. 1973 Feb.

Abstract

Low concentrations of acetaldehyde, similar to those that can occur in the brain of ethanol-treated animals, effectively inhibit the pyruvate dehydrogenase complex purified from ox brain or from ox kidney, although the precise mechanism of this inhibition remains to be defined.

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