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. 1973 Aug 31;181(4102):845-7.
doi: 10.1126/science.181.4102.845.

Human chorionic gonadotropin: its possible role in maternal lymphocyte suppression

E W Adcock 3rd, T Teasdale, C S August, S Cox, G Meschia, T C Ballaglia, M A Naughton

Human chorionic gonadotropin: its possible role in maternal lymphocyte suppression

E W Adcock 3rd et al. Science. .

Abstract

Human chorionic gonadotropin completely inhibits the response of lymphocytes to phytohemagglutinin. The effect is both reversible and noncytotoxic. These observations support the theory that the fetus is accepted because human chorionic gonadotropin represents trophoblastic surface antigen and blocks the action of maternal lymphocytes.

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