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. 1979 Sep 28;205(4413):1397-9.
doi: 10.1126/science.472755.

Meiotic maturation in Xenopus laevis oocytes initiated by insulin

M El-Etr, S Schorderet-Slatkine, E E Baulieu

Meiotic maturation in Xenopus laevis oocytes initiated by insulin

M El-Etr et al. Science. .

Abstract

Insulin can induce meiotic division in Xenopus laevis oocytes. This effect shows the specificity expected of a receptor-mediated mechanism. It is potentiated by ethynylestradiol, a steroid antagonist of pregesterone (the natural hormone that provokes meiosis). The Xenopus laevis oocytes may serve as a model for the study of the poorly understood effect of insulin on cell division.

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