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Comparative Study
. 1973 Apr;25(4):524-7.
doi: 10.1128/am.25.4.524-527.1973.

Evaluation of a red cell agglutination test for detection of Australia antigen (HG Ag)

K H Germain, S K Sturdivant, W A Rightsel
Comparative Study

Evaluation of a red cell agglutination test for detection of Australia antigen (HG Ag)

K H Germain et al. Appl Microbiol. 1973 Apr.

Abstract

An investigational red cell agglutination (RCA) test was evaluated for sensitivity in detecting and titering hepatitis B antigen (HB Ag) in comparison with two counterelectrophoresis (CEP) systems and a solid-phase radioimmunoassay (RIA). The RCA procedure was found to be significantly more sensitive than the CEP methods and compares favorably in sensitivity with the solid-phase RIA, detecting even lower concentrations of the HB Ag. Since the RCA test can be completed in 2 to 3 h and requires relatively inexpensive equipment, it offers a highly sensitive and rapid procedure suitable for use in blood banks to screen donors or detect low levels of antigen in serum of patients.

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References

    1. Ann Intern Med. 1967 May;66(5):924-31 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Jul;60(3):814-21 - PubMed
    1. J Immunol. 1970 Apr;104(4):1031-4 - PubMed
    1. J Infect Dis. 1970 May;121(5):550-4 - PubMed
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