Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration
- PMID: 4735595
- DOI: 10.1126/science.180.4085.511
Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration
Abstract
Neurofibrillary degeneration is an important pathological finding in senile and presenile dementia of the Alzheimer type. Experimentally, aluminum induces neurofibrillary degeneration in neurons of higher mammals. Aluminum concentrations approaching those used experimentally have been found in some regions of the brains of patients with Alzheimer's disease.
Similar articles
-
Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration.Trans Am Neurol Assoc. 1973;98:17-20. Trans Am Neurol Assoc. 1973. PMID: 4784929 No abstract available.
-
Intranuclear aluminum content in Alzheimer's disease, dialysis encephalopathy, and experimental aluminum encephalopathy.Acta Neuropathol. 1980;50(1):19-24. doi: 10.1007/BF00688530. Acta Neuropathol. 1980. PMID: 7376825
-
Effect of aluminum upon conditioned avoidance response acquisition in the absence of neurofibrillary degeneration.Pharmacol Biochem Behav. 1975 Nov-Dec;3(6):1003-9. doi: 10.1016/0091-3057(75)90008-8. Pharmacol Biochem Behav. 1975. PMID: 1223891
-
Aluminum, Alzheimer's disease, and the olfactory system.Ann N Y Acad Sci. 1991;640:8-13. doi: 10.1111/j.1749-6632.1991.tb00183.x. Ann N Y Acad Sci. 1991. PMID: 1776763 Review.
-
Levels of two brain-specific proteins during degeneration and development.UCLA Forum Med Sci. 1971;14:481-9. UCLA Forum Med Sci. 1971. PMID: 4942381 Review. No abstract available.
Cited by
-
Experimental study of biological effects of leads and aluminum following oral administration.Environ Health Perspect. 1979 Jun;30:47-51. doi: 10.1289/ehp.30-1637724. Environ Health Perspect. 1979. PMID: 446457 Free PMC article.
-
Metabolism and possible health effects of aluminum.Environ Health Perspect. 1986 Mar;65:363-441. doi: 10.1289/ehp.8665363. Environ Health Perspect. 1986. PMID: 2940082 Free PMC article. Review.
-
Altered cytokeratin expression and differentiation induction during neoplastic transformation of cultured rat liver cells by nickel subsulfide.Cell Biol Toxicol. 1989 Nov;5(3):271-86. doi: 10.1007/BF01795356. Cell Biol Toxicol. 1989. PMID: 2480838
-
Aluminium and calcium in soil and food from Guam, Palau and Jamaica: Implications for amyotrophic lateral sclerosis and parkinsonism-dementia syndromes of Guam.Environ Geochem Health. 1989 Jun;11(2):45-53. doi: 10.1007/BF01782992. Environ Geochem Health. 1989. PMID: 24202289
-
Immunocytochemical and ultrastructural evidence of dendritic degeneration in motor neurons of aluminum-intoxicated rabbits.Acta Neuropathol. 1993;85(2):122-8. doi: 10.1007/BF00227758. Acta Neuropathol. 1993. PMID: 8442404
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources