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. 1975 Jan 25;1(7900):195-7.
doi: 10.1016/s0140-6736(75)91361-6.

Common variable immunodeficiency, Hodgkin's disease, and other malignancies in a Newfoundland family

S K Buehler, F Firme, G Fodor, G R Fraser, W H Marshall, P Vaze

Common variable immunodeficiency, Hodgkin's disease, and other malignancies in a Newfoundland family

S K Buehler et al. Lancet. .

Abstract

A large inbred family is described in which there were seven cases of Hodgkin's disease, three of lymphosarcoma, two of thymoma, two of common variable immunodeficiency, and single cases of retinoblastoma, neuroblastoma, and rhabdomyosarcoma. There have been no other lymphoma cases in the community during the past decade. Further study of this family may help to define the genetic basis for development of Hodgkin's disease and other disorders.

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