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. 1973 Oct 19;182(4109):287-91.
doi: 10.1126/science.182.4109.287.

Complete amino acid sequence of the Mu heavy chain of a human IgM immunoglobulin

F W Putnam, G Florent, C Paul, T Shinoda, A Shimizu

Complete amino acid sequence of the Mu heavy chain of a human IgM immunoglobulin

F W Putnam et al. Science. .

Abstract

The amino acid sequence of the micro, chain of a human IgM immunoglobulin, including the location of all disulfide bridges and oligosaccharides, has been determined. The homology of the constant regions of immunoglobulin micro, gamma, alpha, and epsilon heavy chains reveals evolutionary relationships and suggests that two genes code for each heavy chain.

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