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. 1973 Aug;14(8):627-30.
doi: 10.1136/gut.14.8.627.

Inheritance and influence of histocompatibility (HL-A) antigens in adult coeliac disease

P L Stokes, P Asquith, G K Holmes, P MacKintosh, W T Cooke

Inheritance and influence of histocompatibility (HL-A) antigens in adult coeliac disease

P L Stokes et al. Gut. 1973 Aug.

Abstract

In a study of histocompatibility antigens in adult coeliac disease the HL-A phenotypes have been determined in 117 patients and 149 of their first-degree relatives, of whom 94 had had a jejunal biopsy performed. There was an increased frequency of the HL-A 8 antigen in the patients and their relatives. Family studies showed no irregularity in the inheritance of both this antigen and the HL-A 1 and 8 haplotype.

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