Chromosome studies in induced abortions
- PMID: 4747809
- DOI: 10.1111/j.1399-0004.1973.tb01927.x
Chromosome studies in induced abortions
Abstract
PIP: Chromosome studies of 172 cases of induced abortions during 1967-1972 in Denmark using 212 cultures from fetal skin, placenta, and amniotic fluid cells showed 6 (3.48%) fetuses with aberations. The aberrations were: two 47, XY+C; one 47, XY+E; one 47, XY+G; one 46, XX/47, XX,+C; and one 46, XX/47, XX,+G. Besides these aberrations, tetraploidy was observed in cultures from amniotic fluid and membranes in frequencies up to 10%. Only 1 case of aberration was found in maternal age groups of less than 34 years (.7%) as opposed to 3 cases (27%) in 40+ groups. Average maternal age for total material was 26.5 years and for aberrations 33.6 years. Average gestational age was 12 1/2 weeks, with 10 1/2 weeks for aberrations. Sex ratio of males to females was .88 for abortions of the first trimester and 1.30 for second trimester.
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