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. 1973 Oct 27;4(5886):208-11.
doi: 10.1136/bmj.4.5886.208.

Prostaglandin 15 (R) 15-methyl-E2 methyl ester for suppression of gastric acidity in gravida at term

J J Amy, D M Jackson, P A Ganesan, S M Karim

Prostaglandin 15 (R) 15-methyl-E2 methyl ester for suppression of gastric acidity in gravida at term

J J Amy et al. Br Med J. .

Abstract

During the second hour after giving 100 mug of orally administered prostaglandin 15 (R) 15-methyl-E(2) methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E(2) methyl ester could prove of value in the preoperative preparation of the pregnant patient before anaesthesia for reducing the incidence of acid regurgitation.

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