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. 1973 Nov;135(3):469-81.
doi: 10.1042/bj1350469.

Enzymic mechanisms involving concomitant transfer and hydrolysis reactions

J M Frère

Enzymic mechanisms involving concomitant transfer and hydrolysis reactions

J M Frère. Biochem J. 1973 Nov.

Abstract

The kinetic parameters of ten different enzymic mechanisms in which bimolecular transfer reactions occur concomitantly with the hydrolysis of the donor molecule have been studied. The usefulness of these parameters for making a choice of mechanism is discussed. The analysis has been extended to the use of alternative substrates in bimolecular transfer reactions that proceed without the hydrolysis of the donor molecule.

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