Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Mar 29;1(5960):714-6.
doi: 10.1136/bmj.1.5960.714.

Serum alpha - fetoprotein levels in patients with cystic fibrosis and their parents and siblings

R K Chandra, K Madhavankutty, R C Way

Serum alpha - fetoprotein levels in patients with cystic fibrosis and their parents and siblings

R K Chandra et al. Br Med J. .

Abstract

Patients with cystic fibrosis (C.F.) showed raised serum levels of alpha-fetoprotein (AFP). A moderate but significant increase in serum AFP was present in their parents and some siblings. There was no correlation between the clinical severity of the disease and serum AFP concentration. Samples from control groups with gluten-induced malabsorption and bronchiectasis had normal levels. Persistent synthesis of AFP may be an associated marker of C.F. genes, and estimation of serum AFP might help in detecting heterozygote carriers in families at risk.

PubMed Disclaimer

References

    1. Adv Cancer Res. 1971;14:295-358 - PubMed
    1. Lancet. 1972 Jul 29;2(7770):197-9 - PubMed
    1. Lancet. 1972 Nov 25;2(7787):1112-5 - PubMed
    1. Lancet. 1973 Aug 18;2(7825):385 - PubMed
    1. Lancet. 1973 Oct 27;2(7835):923-4 - PubMed

LinkOut - more resources