Chromosome markers in Mus musculus: strain differences in C-banding
- PMID: 4778788
- PMCID: PMC1213039
- DOI: 10.1093/genetics/75.4.663
Chromosome markers in Mus musculus: strain differences in C-banding
Abstract
The mitotic chromosomes of several inbred strains of mice and a series of F(1) hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F(1) hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.
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