Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Aug 15;35(8):997-8.
doi: 10.1007/BF01949903.

Changes in the activities of protein kinase modulators in the cerebellum of mice due to ethanol, caffeine, or phenobarbital administration

W N Kuo, J L Williams, T Floyd-Jones, C F Duggans, D L Boone, S O Smith, R F Copeland

Changes in the activities of protein kinase modulators in the cerebellum of mice due to ethanol, caffeine, or phenobarbital administration

W N Kuo et al. Experientia. .

Abstract

Decreased activities of both the inhibitory modulator of adenosine 3':5'-monophosphate (cAMP)-dependent protein kinase (A-PK) as well as the stimulatory modulator of guanosine 3':5'-monophosphate (cGMP)-dependent protein kinase (G-PK) from the mouse cerebellum were noted due to the administration of excessive doses of ethanol, caffeine, and phenobarbital for up to 28 days. The dose-dependent of the inhibition of A-PK or the stimulation of G-PK was observed as a function of the amount of protein kinase modulators in the cerebellum of mice receiving different doses of ethanol.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Biochim Biophys Acta. 1976 Jun 23;437(1):142-9 - PubMed
    1. Res Commun Chem Pathol Pharmacol. 1977 Jun;17(2):215-24 - PubMed
    1. J Biol Chem. 1978 Apr 25;253(8):2518-21 - PubMed
    1. Biochem Biophys Res Commun. 1975 Aug 18;65(4):1214-20 - PubMed
    1. Biochem J. 1974 Feb;138(2):195-9 - PubMed

Publication types