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. 1973 Dec;28(6):589-91.
doi: 10.1038/bjc.1973.190.

Methotrexate in liver and bile after intravenous dosage in man

P J Creaven, H H Hansen, D A Alford, L M Allen
Free PMC article

Methotrexate in liver and bile after intravenous dosage in man

P J Creaven et al. Br J Cancer. 1973 Dec.
Free PMC article

Abstract

Measurements of methotrexate have been made in the liver and plasma of 4 patients and in the bile and plasma of 1 patient receiving [(3)H]methotrexate. Projections from a theoretical model of concentration of methotrexate in liver are confirmed but projections of biliary excretion are not.

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