Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jul 15;24(1):49-52.
doi: 10.1002/ijc.2910240109.

Enhancement of carcinoembryonic antigen expression by interferon

A M Attallah, C F Needy, P D Noguchi, B L Elisberg

Enhancement of carcinoembryonic antigen expression by interferon

A M Attallah et al. Int J Cancer. .

Abstract

Human interferon decreased DNA but not RNA synthesis in a human colon carcinoma cell line, WiDr; in addition, there was a two- to three-fold increase in the expression of a tumor-associated antigen, carcinoembryonic antigen. In contrast, interferon had no effect on a normal human diploid cell line, WI-38. Thus, in addition to its anti-cellular effect against tumor cells, interferon can also modulate tumor antigenicity.

PubMed Disclaimer

LinkOut - more resources