Cephamycins, a new family of beta-lactam antibiotics. II. Isolation and chemical characterization
- PMID: 4790553
- PMCID: PMC444279
- DOI: 10.1128/AAC.2.3.132
Cephamycins, a new family of beta-lactam antibiotics. II. Isolation and chemical characterization
Abstract
Cephamycins A and B were isolated from the same fermentation broth of various actinomycetes by adsorption and ion-exchange methods. The antibiotics were separated from each other by column chromatography on a dextran-based ion-exchange resin. Cephamycin C was isolated from a different fermentation broth by ion-exchange and gel-filtration methods. The chemical characteristics of these new antibiotics were determined.
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