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Case Reports
. 1975 Apr 26;1(7913):953-4.
doi: 10.1016/s0140-6736(75)92010-3.

Lymphocyte-dependent antibody and renal graft rejection

C R Stiller, N R Sinclair, S Abrahams, R A Ulan, M Fung, A C Wallace
Case Reports

Lymphocyte-dependent antibody and renal graft rejection

C R Stiller et al. Lancet. .

Abstract

A patient with preformed cytotoxic lymphocyte-dependent antibody (L.D.A.) against the specific renal transplant donor rapidly rejected the grafted kidney. The characteristics of rejection were not those of hyperacute rejection due to cytotoxic complement-dependent antibody or of acute rejection is attributed to the cytotoxic activity of L.D.A. The avoidance of transplants based on positive crossmatches by the L.D.A. test or at least the carrying out of the L.D.A. crossmatch is advised.

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