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. 1979 Feb 9;23(3):143-52.
doi: 10.1007/BF00219453.

Action of staphylococcal alpha-toxin on membranes: some recent advances

Action of staphylococcal alpha-toxin on membranes: some recent advances

S Harshman. Mol Cell Biochem. .

Abstract

Recent developments in the area of Staphylococcal alpha-toxin studies are presented which modify the concepts previously held with respect to both biological and physical properties of alpha-toxin. New data concerning the nature of the binding site for alpha-toxin on rabbit erythrocyte membranes and a model to explain the various observed complexes of alpha-toxin and membrane receptor are discussed. Finally, evidence suggesting that Staphylococcal alpha-toxin is a potent demyelinating agent is presented.

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