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Clinical Trial
. 1979 Jun;55(644):393-5.
doi: 10.1136/pgmj.55.644.393.

Cimetidine in the prevention of gastric ulcer relapse

R J Machell, P J Ciclitira, M J Farthing, A P Dick, J O Hunter
Clinical Trial

Cimetidine in the prevention of gastric ulcer relapse

R J Machell et al. Postgrad Med J. 1979 Jun.

Abstract

Twenty-five patients with healed gastric ulcers completed an 11-month double-blind controlled trial comparing cimetidine 1 g daily with placebo in the prevention of ulcer relapse. Ulcers recurred in 14 patients, 12 on placebo, 2 on cimetidine. In 11 patients, 9 on cimetidine, 2 on placebo, the ulcers remained healed at the end of the trial (P less than 0.002). Cimetidine 1 g daily significantly reduces the relapse rate in gastric ulceration.

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