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. 1974 Apr;27(4):777-83.
doi: 10.1128/am.27.4.777-783.1974.

Production of a potent vaccine from the attenuated M-44 strain of Coxiella burneti

D M Robinson, S E Hasty

Production of a potent vaccine from the attenuated M-44 strain of Coxiella burneti

D M Robinson et al. Appl Microbiol. 1974 Apr.

Abstract

The attenuated M-44 strain of Coxiella burneti was heated to free it of adventitious agents that may have been present. Parallel titrations of the strain before and after heating indicated that the virulence for guinea pigs was markedly decreased. Guinea pigs immunized with the strain derived after heat treatment were protected from the effects of challenge with C. burneti in either phase I or II.

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References

    1. Am J Hyg. 1951 May;53(3):326-31 - PubMed
    1. Proc Soc Exp Biol Med. 1970 Dec;135(3):706-8 - PubMed
    1. J Immunol. 1962 Jan;88:100-8 - PubMed
    1. J Bacteriol. 1961 May;81(5):794-9 - PubMed
    1. Stain Technol. 1964 May;39:135-40 - PubMed

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