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Comparative Study
. 1975 Jun 1;122(3):313-5.
doi: 10.1016/0002-9378(75)90175-1.

Prenatal detection of neural tube defects. Comparison between alpha-fetoprotein and beta-trace protein assays

A Milunsky, J N Macri, R R Weiss, E Alpert, D G McIsaac, M S Joshi
Comparative Study

Prenatal detection of neural tube defects. Comparison between alpha-fetoprotein and beta-trace protein assays

A Milunsky et al. Am J Obstet Gynecol. .

Abstract

The prenatal diagnosis of neural tube defects is now possible in about 90 per cent of cases by assaying the amniotic fluid for alpha fetoprotein. The accuracy of beta-trace protein assays on amniotic fluid samples from defective fetuses was compared to alpha-fetoprotein studies. At present, alpha-fetoprotein studies provide more reliable results.

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