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. 1974 Jul 26;185(4148):360-1.
doi: 10.1126/science.185.4148.360.

Immediate hypersensitivity responses in flatfish

Immediate hypersensitivity responses in flatfish

T C Fletcher et al. Science. .

Abstract

Fungal extracts that precipitate with human C-reactive protein caused immediate erythema on subdermal injection into marine flatfish. Only species with calcium-dependent serum precipitins to these fungi showed skin reactions. Immediate hypersensitivity in a nonreactive species could be induced after injection with serum from reactive species. The transferable serum factor (or factors) was heat sensitive.

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