[Acid polysaccharides (glycosaminoglycans) of the articular cartilage in rheumatoid arthritis]

Abstract

As a result of histochemical investigation of the articular hyaline cartilage in 22 pateints with rheumatoid arthritis data were obtained on the decrease and redistribution of acid polysaccharides glycosamine glucane including keratosulphates, which led to an impartment of the cartilage supply and development therein of destructive processes. It was established that the most pronounced changer occurred in the main substance of the cartilage; changes in chondrocytes, according to the authors, were of secondary nature.