Rat tumour allografts evoke anaphylactic antibody responses
- PMID: 48504
- PMCID: PMC1445886
Rat tumour allografts evoke anaphylactic antibody responses
Abstract
In vitro assays of release of histamine from peritoneal mast cells showed that Wistar rats produced anaphylactic antibody in response to a single immunization with an allogeneic sarcoma. The response occurs early after immunization, and no adjuvant is needed. The thermolability of the anaphylactic antibody suggests that it is IgE.
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