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. 1975 Jun 4;109(1):37-42.
doi: 10.1016/s0021-9673(01)81015-3.

Characterisation and quantitation of morphine in urine using high-pressure liquid chromatography with fluorescence detection

I Jane, J F Taylor

Characterisation and quantitation of morphine in urine using high-pressure liquid chromatography with fluorescence detection

I Jane et al. J Chromatogr. .

Abstract

A simple and rapid method for the identification and quantitation of morphine in urine samples is described. The procedure, which involves conversion of the drug a fluorescent product followed by liquid chromatography, is shown to be highly sensitive and specific. Levels down to 0.01 mug/ml of morphine can be quantitatively detected in urine. A large number of drugs have been tested and shown not to interfere.

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