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. 1974 Feb;27(2):423-4.
doi: 10.1128/am.27.2.423-424.1974.

In vitro metabolism of T-2 toxin

R A Ellison, F N Kotsonis

In vitro metabolism of T-2 toxin

R A Ellison et al. Appl Microbiol. 1974 Feb.

Abstract

Incubation of T-2 toxin with the 9,000 x g supernatant fluid of both human and bovine liver homogenate resulted in conversion to a single, deacetylated product identified as HT-2 toxin. Metabolism is more rapid in human liver. HT-2 toxin was not produced when human plasma was the incubating medium nor was it produced by treatment of T-2 toxin with simulated gastric juice. T-2 toxin was stable in gastric juice for at least 1 h.

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References

    1. Biochem Biophys Res Commun. 1971 Oct 15;45(2):396-401 - PubMed
    1. Appl Microbiol. 1973 Apr;25(4):699-704 - PubMed
    1. Appl Microbiol. 1973 Oct;26(4):540-3 - PubMed

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