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. 1974 Aug;14(2):307-14.
doi: 10.1128/JVI.14.2.307-314.1974.

Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose

H Ludwig, H Becht, R Rott

Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose

H Ludwig et al. J Virol. 1974 Aug.

Abstract

Pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by Concanavalin A added early after infection. The infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. Sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-Deoxy-d-glucose reversibly disturbs virus-induced fusion and reduces significantly the virus infectivity.

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References

    1. J Gen Virol. 1968 May;2(3):357-64 - PubMed
    1. J Exp Med. 1968 Nov 1;128(5):1011-20 - PubMed
    1. J Virol. 1968 Oct;2(10):1172-84 - PubMed
    1. Virology. 1970 Feb;40(2):410-2 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Jul;66(3):799-806 - PubMed

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