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. 1979 Apr 15;180(1):245-8.
doi: 10.1042/bj1800245.

Taurine transport in renal brush-border-membrane vesicles

R Rozen, H S Tenenhouse, C R Scriver

Taurine transport in renal brush-border-membrane vesicles

R Rozen et al. Biochem J. .

Abstract

Taurine transport in isolated brush-border-membrane vesicles from rat kidney is concentrative and it is driven by the Na+ gradient and transmembrane potential difference; binding is not a significant component of net uptake. The Na+-dependent component of net uptake is saturable with an apparent Km of 17 microM. The taurine-transport mechanism is selective for beta-amino compounds.

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