Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Apr 15;180(1):37-44.
doi: 10.1042/bj1800037.

Application of spin-echo nuclear magnetic resonance to whole-cell systems. Membrane transport

K M Brindle, F F Brown, I D Campbell, C Grathwohl, P W Kuchel

Application of spin-echo nuclear magnetic resonance to whole-cell systems. Membrane transport

K M Brindle et al. Biochem J. .

Abstract

A new method for studying membrane transport is presented. High resolution n.m.r. is used to measure the distribution of small molecules between the intracellular and extracellular compartments. The method uses spin-echo techniques and relies on a difference in the magnetic susceptibility of the media inside and outside of cells. It also provides simultaneous information on the metabolic status of the cell. The method is illustrated by a study of alanine and lactate transport in the human erythrocyte.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Biol Chem. 1964 Mar;239:872-8 - PubMed
    1. J Physiol. 1962 Mar;160:392-403 - PubMed
    1. Biochim Biophys Acta. 1978 Apr 4;508(2):364-9 - PubMed
    1. FEBS Lett. 1977 Oct 1;82(1):12-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 Feb;75(2):891-5 - PubMed