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. 1979 Jun 15;180(3):669-72.
doi: 10.1042/bj1800669.

Effects of the cyanine dye 3,3'-dipropylthiocarbocyanine on mitochondrial energy conservation

P H Howard Jr, S B Wilson

Effects of the cyanine dye 3,3'-dipropylthiocarbocyanine on mitochondrial energy conservation

P H Howard Jr et al. Biochem J. .

Abstract

Mitochondrial respiration and oxidative phosphorylation were inhibited by the membrane potential probe 3,3'-dipropylthiocarbocyanine [diS-C3-(5)]. Evidence is presented that suggests that the dye acts as both an inhibitor of electron transport and an uncoupler of oxidative phosphorylation.

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