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. 1975 May 3;1(7914):1003-5.
doi: 10.1016/s0140-6736(75)91947-9.

Abnormal leucocyte composition and sodium transport in essential hypertension

R P Edmondson, R D Thomas, P J Hilton, J Patrick, N F Jones

Abnormal leucocyte composition and sodium transport in essential hypertension

R P Edmondson et al. Lancet. .

Abstract

Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.

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