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. 1968 May;95(5):1587-90.
doi: 10.1128/jb.95.5.1587-1590.1968.

In vitro activity of carbenicillin against gram-negative bacilli

G P Bodey, L M Terrell

In vitro activity of carbenicillin against gram-negative bacilli

G P Bodey et al. J Bacteriol. 1968 May.

Abstract

The activity of a new semisynthetic penicillin, carbenicillin, was determined against 241 strains of gram-negative bacilli with the tube-dilution technique. Of 143 strains of Pseudomonas sp., 99 had a minimal inhibitory concentration of 200 to 300 mug/ml. The majority of strains of Escherichia coli and Proteus spp. were sensitive to this antibiotic, with minimal inhibitory concentrations of 25 mug/ml or less. Strains of Klebsiella sp. were quite resistant to carbenicillin. The size of inoculum had no significant effect on the minimal inhibitory concentration for Pseudomonas sp.

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References

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    1. Nature. 1967 Jul 1;215(5096):25-30 - PubMed
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