doi: 10.1007/BF03006447.
Ventilation and chemoreflexes during enflurane sedation and anaesthesia in man
- PMID: 487229
- DOI: 10.1007/BF03006447
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Ventilation and chemoreflexes during enflurane sedation and anaesthesia in man
Can Anaesth Soc J.
1979 Sep.
Abstract
Enflurane sedation and anaesthesia in healthy fit subjects reduced ventilation and the response to carbon dioxide, hypoxaemia and a low dose of doxapram, all in a dose-related fashion. Comparing the three chemoreflexes tested, the response to hypoxaemia and doxapram were the more profoundly impaired; they were nearly totally abolished by anaesthesia. These effects of enflurane on chemoreflex activities are qualitatively similar to those previously observed with halothane.
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