Changes in the proportion of guinea-pig gamma-1 and gamma-2 antibodies during immunization and the cellular localization of these immunoglobulins
- PMID: 4872344
- PMCID: PMC1409405
Changes in the proportion of guinea-pig gamma-1 and gamma-2 antibodies during immunization and the cellular localization of these immunoglobulins
Abstract
Guinea-pigs immunized with DNP—BSA first produced anti-DNP antibodies of the γ2-class followed by anti-DNP antibodies of the γ1-class. The cellular localization of γ2 and γ1 immunoglobulins was investigated by immunofluorescence techniques during this shifting period. The γ2- and γ1-classes of immunoglobulins were, with few possible exceptions, produced in separate cells.
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