doi: 10.1126/science.161.3842.706.
Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe
- PMID: 4874578
- DOI: 10.1126/science.161.3842.706
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Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe
Science.
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Abstract
Units in areas of the midbrain rich in neurons containing serotonin respond to parenteral injections of d-lysergic acid diethylamide by a reversible cessation of spontaneous activity. The dose required is at or below threshold for gross behavioral effects. An inhibition of neurons containing serotonin after administration of d-lysergic acid diethylamide could account for the decreased metabolism of serotonin produced by this drug.
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